H-2Kd/Human MAGE-A3 (SYVKVLHHM) MHC Monomer

CAT#: MHC-YF206

This product is a MHC monomer of biotinylated peptide/MHC complex composed MAGE-A3-derived peptide of SYVKVLHHM sequence and H-2Kd molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, K-562, OE19, PC-3, SH-SY5Y, SK-BR-3, U-266/70, U-266/84)

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • MAGE-A3
  • Antigen Species
  • Human
  • Peptide
  • SYVKVLHHM
  • Conjugate
  • Biotin

Target

  • Antigen Introduction
  • This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
  • Alternative Names
  • MAGEA3; MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6
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