Human TCR recognizes C32 Phosphomycoketide peptide (C32 phosphomycoketide) in the context of human CD1c. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR. Please note that the activity is not guaranteed.

Specifications

Host Species
Human

Target
C32 Phosphomycoketide

Species Reactivity
Mycobacterium tuberculosis

Epitope
C32 phosphomycoketide

MHC
human CD1c

Type
Soluble TCR (ZIP-Fos/ZIP-Jun)

Related Disease
Infectious disease

TCR Expression Strategy
ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

Target

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