Human TCR recognizes gag-pol peptide (KRWIIMGLNK) in the context of HLA-B∗2705. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR. Please note that the activity is not guaranteed.

Specifications

Host Species
Human

Target
gag-pol

Species Reactivity
HIV1

Epitope
KRWIIMGLNK

MHC
HLA-B∗2705

Type
Soluble TCR (ZIP-Fos/ZIP-Jun)

TCR Expression Strategy
ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

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MHC Tetramer Products for Virology

CAT	Product Name	Application	Type
MHC-YF224	A*02:01/HIV pol (ILKEPVHGV) MHC Monomer	MHC Multimer
MHC-YF668	A*02:01/HIV Pol (VIYHYVDDL) MHC Pentamer	FCM

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