Recombinant Human Anti-SREBF1 Soluble TCR (FB6) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2393)
Human TCR (FB6) recognizes SREBF1 peptide (YLQDSLATT) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (FB6). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43878/1319_F1_4_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43878/1319_F1_4_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5406/639_A4_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5406/639_A4_2_selected.jpg
Figure 3 Adrenal gland
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_B_6_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_B_6_5.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_5.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (RPMI-8226, SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072310-SREBF1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072310-SREBF1
Specifications
- Host Species
- Human
- Target
- SREBF1
- Species Reactivity
- Human
- Epitope
- YLQDSLATT
- MHC
- HLA-A2
- Clone
- FB6
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Sterol Regulatory Element Binding Transcription Factor 1; Class D Basic Helix-Loop-Helix Protein 1; SREBP1; BHLHd1; Sterol Regulatory Element-Binding Transcription Factor 1; Sterol Regulatory Element-Binding Protein 1; SREBP-1
- Gene ID
- 6720
- UniProt ID
- P36956
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IgG Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2921z | Mouse Anti-SREBF1 Recombinant Antibody (clone 15H9) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MOB-1939CT | Recombinant Mouse anti-Human SREBF1 Monoclonal antibody (EML2093) | WB |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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