Recombinant Human Anti-SREBF1 Soluble TCR (FB6) (C-Cys) (CAT#: VS-0622-YF5101)
Human TCR (FB6) recognizes SREBF1 peptide (YLQDSLATT) in the context of HLA-A2. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43878/1319_F1_4_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43878/1319_F1_4_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5406/639_A4_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5406/639_A4_2_selected.jpg
Figure 3 Adrenal gland
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_B_6_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_B_6_5.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_5.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43343/132102_A_8_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (RPMI-8226, SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072310-SREBF1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072310-SREBF1
Specifications
- Host Species
- Human
- Target
- SREBF1
- Species Reactivity
- Human
- Epitope
- YLQDSLATT
- MHC
- HLA-A2
- Clone
- FB6
- Type
- Soluble TCR (C-Cys)
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Sterol Regulatory Element Binding Transcription Factor 1; Class D Basic Helix-Loop-Helix Protein 1; SREBP1; BHLHd1; Sterol Regulatory Element-Binding Transcription Factor 1; Sterol Regulatory Element-Binding Protein 1; SREBP-1
- Gene ID
- 6720
- UniProt ID
- P36956
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IgG Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2921z | Mouse Anti-SREBF1 Recombinant Antibody (clone 15H9) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MOB-1939CT | Recombinant Mouse anti-Human SREBF1 Monoclonal antibody (EML2093) | WB |
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