β2GPI

β2-Glycoprotein I (β2GPI) is a multi-domain glycoprotein that plays a crucial role in the regulation of coagulation and the immune response. It is primarily found in the plasma and is known for its involvement in antiphospholipid syndrome, a disorder characterized by the presence of antiphospholipid antibodies that can lead to thrombosis and pregnancy complications. β2GPI is also recognized for its ability to bind negatively charged phospholipids, thus participating in various physiological and pathological processes.