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For Research Use Only. Not For Clinical Use.
Enzymes, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (Proximal enterocytes, Distal enterocytes, Late spermatids)
Low immune cell specificity
Low cell line specificity
Homodimer (By similarity). (Microbial infection) Interacts with human immunodeficiency virus (HIV-1) Nef (via middle region); this interaction enhances ACOT8 Acyl-CoA thioesterase activity and occurs in a Nef myristoylation-independent manner (PubMed:9299485). According to a second report, the interaction with HIV-1 Nef occurs in a Nef myristoylation-independent manner but does not enhance ACOT8 Acyl-CoA thioesterase activity (PubMed:9153233).
Hydrolase, Serine esterase