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Anti-ADAM9 Recombinant Antibody Products

Anti-ADAM9 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs offers a full range of anti-ADAM9 recombinant antibodies with excellent performance to ensure global customers’ projects execute smoothly.

ADAM9: A Promising Target in Cancer Therapy

ADAM9 (A Disintegrin and Metalloprotease 9) is a crucial membrane-anchored protein implicated in multiple physiological processes. Increasing evidence demonstrated that elevated ADAM9 expression has been linked to numerous cancers, often associated with increased tumor aggressiveness and poor patient outcomes. Moreover, ADAM9 promotes tumor progression, resistance to therapies, and tumor metastasis through proteolytic or non-proteolytic processes. Given its significant role in oncogenesis, the development of targeted therapies against ADAM9 is paramount for advancing cancer treatment.

Alternative Names

ADAM Metallopeptidase Domain 9; A Disintegrin And Metalloproteinase Domain 9; ADAM 9; Meltrin-gamma; Cellular disintegrin-related protein; Metalloprotease/disintegrin/cysteine-rich protein 9; Mltng; MDC9; KIAA0021; CORD9; Cone Rod Dystrophy 9; MCMP; Myeloma cell metalloproteinase.

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Pancreatic endocrine cells)

Immune cell specificity

Immune cell enhanced (classical monocyte)

Cell line specificity

Low cell line specificity

Interaction

Interacts with SH3GL2 and SNX9 through its cytoplasmic tail (PubMed:10531379). Interacts with ITGA6.

Molecular function

Hydrolase, Metalloprotease, Protease

More Types Infomation

Anti-ADAM9 Recombinant Antibody Products

Based on our robust platform, we develop and provide multiple types of premium anti-ADAM9 recombinant antibody products for customers to select for their significant projects. We are dedicated to providing top-notch research tools and unmatched technical assistance to help our customers make breakthrough discoveries and achieve their scientific objectives easily and efficiently.

Cat. No. Product Name Target Species Host Species Applications
TAB-0551CL Mouse Anti-ADAM9 Recombinant Antibody Human Mouse IgG ELISA, IP, FuncS
HPAB-N0314-YC Human Anti-ADAM9 Recombinant Antibody Human, Cynomolgus monkey Human IgG ELISA, FC, IHC
VS-0723-WK185 Rabbit Anti-ADAM9 Recombinant Antibody Human Rabbit IgG ELISA, FC
HPAB-N0314-YC-F(E) Human Anti-ADAM9 Recombinant Antibody; Fab Fragment Human, Cynomolgus monkey Human Fab ELISA, FC, IHC
HPAB-N0314-YC-S(P) Human Anti-ADAM9 Recombinant Antibody; scFv Fragment Human, Cynomolgus monkey Human scFv ELISA, FC, IHC

Creative Quality Control

We are dedicated to empowering the biopharmaceutical industry by driving research and development forward with world-class product quality and exceptional customer support. By adhering to a stringent quality management system, we ensure our products exceed industry benchmarks. This not only facilitates a more efficient drug development process but also delivers outstanding value to our clients, ensuring their satisfaction and success.

Customer Reviews

Excellent
Sc***n
Mouse Anti-ADAM9 Recombinant Antibody (clone 3E6) (CAT#: MOB-0440MZ)
I used the mouse anti-ADAM9 recombinant antibody for Western blotting experiments, and it delivered rapid results in under an hour. The antibody produced a strong signal in Western blot analysis of human endothelial whole-cell lysates. This antibody showed superior specificity and sensitivity compared to those I had previously used. Its efficiency and reliability have streamlined my experimental workflow considerably.
14/Mar/2019
Excellent
Dr***i
Human Anti-ADAM9 Recombinant Antibody (HPAB-N0314-YC) (CAT#: HPAB-N0314-YC)
I recently used the Human Anti-ADAM9 Recombinant Antibody for IHC on human tissue samples, and I am very impressed with the results. The antibody provided exceptional specificity and sensitivity, allowing for clear and distinct staining of the ADAM9 protein. The tissue sections had minimal background noise, making the target protein easily distinguishable. Furthermore, the antibody demonstrated excellent consistency across multiple experiments. I highly recommend this recombinant antibody to any researcher looking to detect ADAM9 in their IHC assays.
5/Nov/2023
Excellent
Es***i
Mouse Anti-ADAM9 Recombinant Antibody (TAB-0551CL) (CAT#: TAB-0551CL)
The Mouse Anti-ADAM9 Recombinant Antibody is extremely user-friendly. It comes with clear and detailed protocols, which streamlined the integration into my lab routines. Moreover, it's conjugated for various applications, offering versatility whether I need it for ELISA, flow cytometry, or immunoprecipitation. Additionally, the reduced need for repeat experiments due to its reliability means we save both time and resources in the long run.
21/Jan/2024

Anti-ADAM9 Recombinant Antibody Production

Leveraging our cutting-edge mammalian cell expression platform, which operates entirely serum-free, we offer comprehensive services from gene synthesis to the production of antibodies. This enables us to deliver scalable, high-quality anti-ADAM9 recombinant antibodies to global customers. With over five years of expertise in optimizing processes, we guarantee a rapid and economical supply of antibodies in diverse quantities, ensuring quick turnaround times to meet your needs efficiently.

Featured Anti-ADAM9 Recombinant Antibody Production Platforms Fig.1 Anti-ADAM9 recombinant antibody production: Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-ADAM9 recombinant antibody production.

Fig.2 Anti-ADAM9 recombinant antibody production: Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-ADAM9 recombinant antibody production.

Anti-ADAM9 Recombinant Antibody Modalities

Creative Biolabs is committed to offering premium recombinant antibodies with diverse formats such as Fab, scFv, Diabody, etc., to support global customers swiftly reaching your research purposes. Our wealth of experience and expertise in antibody engineering empower us to customize antibody production to your unique requirements.

Fig.3 The production and modalities of full-length anti-ADAM9 recombinant antibody. (Creative Biolabs Original)Fig.3 Full-Length Anti-ADAM9 Recombinant Antibody Production and Modalities

ADAM9-Targeted Drug Information

Table 1. ADAM9-targeted drug information.

Company Highest Phase Drug Type Condition
ImmunoGen (Originator)
MacroGenics
Phase I Drug Conjugates Cancer, colorectal
Cancer, esophagus
Cancer, lung (non-small cell) (NSCLC)
Cancer, pancreas
Cancer, solid tumor
Cancer, stomach
Triple negative breast cancer
MacroGenics (Originator) Preclinical Biologics Cancer, colon
Cancer, lung
ImmunoGen (Originator) Biological Testing Drug Conjugates Cancer
China Medical University (CMU)
DCB-USA
Biological Testing Small Molecules (>500 - 750 Da) Cancer
ImmunoGen (Originator)
MacroGenics (Originator)
Biological Testing Drug Conjugates Cancer
MacroGenics (Originator) Biological Testing Biologics Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

For additional information regarding our anti-ADAM9 recombinant antibody offerings, please feel free to get in touch with us.

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