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ARL2
Anti-ARL2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes.
Protein class
FDA approved drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Proximal tubular cells, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Found in a complex with ARL2, ARL2BP and SLC25A6 (PubMed:30945270). Found in a complex with at least ARL2, PPP2CB, PPP2R1A, PPP2R2A, PPP2R5E and TBCD. Found in a complex with ARL2, ARL2BP and SLC25A4. The GTP-bound form interacts with PDE6D. Interacts with ELMOD2. The GTP-bound form interacts with ARL2BP. Interacts, preferentially in its GDP-bound state, with TBCD (PubMed:10488091, PubMed:10831612, PubMed:11303027, PubMed:11847227, PubMed:17452337, PubMed:18234692, PubMed:18981177, PubMed:19368893, PubMed:27666374). Interacts with UNC119.
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