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BMP4

This gene encodes a member of the bone morphogenetic protein (BMP) family of proteins, which is part of the transforming growth factor-beta (TGF-beta) superfamily. Members of the BMP family play an important role in bone and cartilage development. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. Alternative splicing results in multiple transcript variants.
  • Anti-Human BMP4 VHH Single Domain Antibody (Al) (TAB-0069CL-VHH)

    • Derivation: Phage-display library (VHH library)
    • Type: Single domain antibody (VHH)
    • Application: For in vitro and in vivo research use. Not intended for any applications in human.

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