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CACNB1
Anti-CACNB1 Recombinant Antibody Products
- Rabbit Anti-CACNB1 Recombinant Antibody (clone rN7/18.1) (VS-0422-LC43)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rabbit IgG
- Application: IP, WB, IF
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- Human Anti-CACNB1 Recombinant Antibody (clone hN7/18.1) (VS-0422-LC42)
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- Species Reactivity: Rat, Human, Mouse
- Type: Human IgG1
- Application: IP, WB, IF
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- Rat Anti-CACNB1 Recombinant Antibody (clone rtN7/18.1) (VS-0422-LC41)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rat IgG2b
- Application: IP, WB, IF
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- Mouse Anti-CACNB1 Recombinant Antibody (clone mN7/18.1) (VS-0422-LC40)
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- Species Reactivity: Rat, Human, Mouse
- Type: Mouse IgG2a
- Application: IP, WB, IF
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- Rabbit Anti-CACNB1 Polyclonal Antibody (MRO-1704-CN) (MRO-1704-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, IF
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- Recombinant Mouse Anti-Human CACNB1 Antibody (MOB-1947MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
CACNB1 (Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1) is a Protein Coding gene. The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Diseases associated with CACNB1 include Malignant Hyperthermia and Malignant Hyperthermia Susceptibility.
Protein class
FDA approved drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Excitatory neurons, Skeletal myocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Regulatory subunit of L-type calcium channels that consist of a pore-forming alpha subunit and auxiliary beta, gamma and delta subunits (By similarity). Interacts with CACNA1A, CACNA1B, CACNA1C and CACNA1S (By similarity). Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. Identified in a complex with CACNA1C (PubMed:15615847). Identified in a complex with the L-type calcium channel subunits CACNA1C, CACNA2D1, CACNB1 and one of the gamma subunits (CACNG4, CACNG6, CACNG7, or CACNG8) (By similarity). Part of a L-type calcium channel complex that contains CACNA1D, CACNA2D1 and CACNB1 (PubMed:1309651). Part of a L-type calcium channel complex that contains CACNA1B, CACNA2D1 and CACNB1 (PubMed:8107964). Interacts with JSRP1. Interacts with RYR1 (By similarity). Interacts with CBARP (By similarity).
Molecular function
Calcium channel, Ion channel, Voltage-gated channel
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