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CD109
Anti-CD109 Recombinant Antibody Products
- Mouse Anti-CD109 Recombinant Antibody (clone C-F58) (MOB-0374CT)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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For Research Use Only. Not For Clinical Use.
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
CD markers, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Adipocytes, Basal respiratory cells, Squamous epithelial cells, Hofbauer cells, Suprabasal keratinocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC TERT1, BJ hTERT+)
Interaction
Heterodimer; disulfide-linked. Interacts with TGFB1 and TGFBR1. Forms a heteromeric complex with TGFBR1, TGFBR2 and TGFBR3 in a ligand-independent manner.
Molecular function
Protease inhibitor, Serine protease inhibitor
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