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For Research Use Only. Not For Clinical Use.
Cancer-related genes, CD markers, Plasma proteins
Intracellular, Membrane (different isoforms)
Cell type enhanced (Adipocytes, Endothelial cells, Hepatic stellate cells, Late spermatids, Syncytiotrophoblasts)
Not detected in immune cells
Group enriched (HUVEC TERT2, TIME)
Interacts (via cadherin 5 domain) with PTPRB (By similarity). Interacts with TRPC4 (PubMed:19996314). Interacts with KRIT1 (PubMed:20332120). Interacts with PARD3 (By similarity). Interacts with RTN4 (isoform B) (PubMed:21183689). Interacts with PALS1; the interaction promotes PALS1 localization to cell junctions and is required for CDH5-mediated vascular lumen formation and endothelial cell (PubMed:27466317).