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COL5A1
Anti-COL5A1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
COL5A1 (Collagen Type V Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL5A1 include Ehlers-Danlos Syndrome, Classic Type, 1 and Ehlers-Danlos Syndrome Type 2. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include heparin binding and extracellular matrix structural constituent. An important paralog of this gene is COL11A1.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Fibroblasts, Skeletal myocytes, Leydig cells, Smooth muscle cells, Sertoli cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, fHDF/TERT166, HeLa, HHSteC, SiHa)
Interaction
Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Interacts with CSPG4.
Molecular function
Heparin-binding
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