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CREB5
Anti-CREB5 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Basal prostatic cells, Adipocytes, monocytes)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (HL-60, Karpas-707, U-2 OS, U-2197)
Interaction
Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
Molecular function
Activator, DNA-binding
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
MAPK Signaling Pathway
PPAR Signaling Pathway
TLR Signaling Pathway
TNF Signaling Pathway
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