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CTBP2
Anti-CTBP2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
CTBP2 (C-Terminal Binding Protein 2) is a Protein Coding gene. Diseases associated with CTBP2 include Retinitis Pigmentosa 14 and Deafness, Autosomal Recessive 9. Among its related pathways are Chronic myeloid leukemia and Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription corepressor activity. An important paralog of this gene is CTBP1.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with HIPK2 and ZNF217. Interacts with PRDM16; represses white adipose tissue (WAT)-specific genes expression (By similarity). Interacts with PNN, NRIP1 and WIZ. Interacts with MCRIP1 (PubMed:25728771). (Microbial infection) Interacts with human adenovirus 5 E1A protein; this interaction seems to potentiate viral replication.
Molecular function
Oxidoreductase, Repressor
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