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CTSL
Anti-CTSL Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
CTSL (Cathepsin L) is a Protein Coding gene. Diseases associated with CTSL include Tracheal Cancer and Eccrine Acrospiroma. Among its related pathways are Bacterial infections in CF airways and Primary Focal Segmental Glomerulosclerosis FSGS. Gene Ontology (GO) annotations related to this gene include histone binding and cysteine-type peptidase activity. An important paralog of this gene is CTSV.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Hofbauer cells, Cytotrophoblasts, Extravillous trophoblasts, Hepatic stellate cells, Macrophages)
Immune cell specificity
Group enriched (non-classical monocyte, intermediate monocyte)
Cell line specificity
Cell line enhanced (ASC TERT1, HSkMC)
Interaction
Dimer of a heavy and a light chain linked by disulfide bonds. Interacts with Long isoform of CD74/Ii chain; the interaction stabilizes the conformation of mature CTSL.
Molecular function
Hydrolase, Protease, Thiol protease
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