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CX3CR1
Anti-CX3CR1 Recombinant Antibody Products
- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0622-CN) (HPAB-0622-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human, Cynomolgus monkey
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0623-CN) (HPAB-0623-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human, Cynomolgus monkey
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0624-CN) (HPAB-0624-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Chicken Anti-CX3CR1 Polyclonal IgY (BRD-0146MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: indirect ELISA, WB
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- Chicken Anti-CX3CR1 Polyclonal IgY (BRD-0988MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.
CX3CR1 encodes a receptor for the chemokine CX3CL1 (fractalkine), which is involved in the adhesion and migration of immune cells, particularly monocytes, and T cells. The CX3CR1 receptor is expressed on a variety of immune cells and plays a key role in inflammation and immune surveillance. It is involved in the recruitment of immune cells to sites of infection or injury. Variants in CX3CR1 have been linked to diseases such as atherosclerosis, Alzheimer's disease, and HIV progression.
Protein class
Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets
Predicted location
Membrane
Single cell type specificity
Group enriched (NK-cells, Microglial cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enriched (RPMI-8226)
Interaction
Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or ITGA4:ITGB1. (Microbial infection) Interacts with human respiratory syncytial virus (HRSV) protein G; this interaction modulates host immune response. (Microbial infection) Interacts with HIV-1 envelope polyprotein gp160.
Molecular function
G-protein coupled receptor, Receptor, Transducer
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