Cleaved PARP

Formats

Anti-Cleaved PARP Recombinant Antibody Products

Mouse Anti-Cleaved PARP Recombinant Antibody (clone M4) (ZG-0165J)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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Mouse Anti-Cleaved PARP Recombinant Antibody (ZG-0166J) (ZG-0166J)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IF/ICC, WB, IHC-P
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For Research Use Only. Not For Clinical Use.

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.