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EIF3M
Anti-EIF3M Recombinant Antibody Products
- Mouse Anti-EIF3M Recombinant Antibody (HPAB-682-FY) (HPAB-682-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, Neut
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- Mouse Anti-EIF3M Recombinant Antibody; scFv Fragment (HPAB-682-FY-S(P)) (HPAB-682-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, Neut
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- Mouse Anti-EIF3M Recombinant Antibody; Fab Fragment (HPAB-682-FY-F(E)) (HPAB-682-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, Neut
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis.
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
Molecular function
Initiation factor
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