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EIF4A1
Anti-EIF4A1 Recombinant Antibody Products
- Rabbit Anti-NHP EIF4A1 Recombinant Antibody (VS-1024-XY182) (VS-1024-XY182)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Rabbit IgG
- Application: WB, IF
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For Research Use Only. Not For Clinical Use.
Enables double-stranded RNA binding activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Basal respiratory cells, Basal keratinocytes, Langerhans cells, Suprabasal keratinocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with PAIP1, EIF4E and UPF2. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. May interact with NOM1. Interacts with PDCD4; this interferes with the interaction between EIF4A and EIF4G. Interacts with RBM4. Interacts with DDX3X in an RNA-independent manner (PubMed:18596238). (Microbial infection) Interacts with human cytomegalovirus/HHV-5 protein UL69.
Molecular function
Helicase, Hydrolase, Initiation factor, RNA-binding
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