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EYA2
Anti-EYA2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Glandular and luminal cells, Basal respiratory cells, Oligodendrocyte precursor cells, Basal prostatic cells, Endometrial ciliated cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HBEC3-KT, SCLC-21H, U-266/70, U-266/84)
Interaction
Interacts with DACH2 and SIX1, and probably with SIX2, SIX4 and SIX5. Interacts with CAPN8 (By similarity). Interacts with GNAZ and GNAI2; this precludes interaction with SIX1.
Molecular function
Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase
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