FCGR1A

FCGR1A encodes a receptor that binds the Fc portion of immunoglobulin G (IgG). This receptor is involved in the immune response by mediating phagocytosis and the activation of immune cells like macrophages, neutrophils, and dendritic cells. FCGR1A plays a critical role in the clearance of pathogens and the modulation of inflammatory responses. It is a key player in the immune system's ability to respond to infections and to regulate immune tolerance. Variants in FCGR1A can affect susceptibility to autoimmune diseases and influence responses to infections and vaccines.