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FLT3LG
Anti-FLT3LG Recombinant Antibody Products
- Mouse Anti-FLT3LG Recombinant Antibody (NEUT-846CQ) (NEUT-846CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
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For Research Use Only. Not For Clinical Use.
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Protein class
RAS pathway related proteins
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (T-cells, NK-cells)
Immune cell specificity
Group enriched (T-reg, naive CD4 T-cell, memory CD4 T-cell, MAIT T-cell, naive CD8 T-cell, memory CD8 T-cell, gdT-cell)
Cell line specificity
Cell line enhanced (HDLM-2, U-266/70)
Interaction
Homodimer (isoform 2).
Molecular function
Cytokine
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