FLT3LG

AbPlus Recombinant Antibody Products Functional Antibody Products Formats

Anti-FLT3LG Recombinant Antibody Products

Hi-Affi™ Rabbit Anti-FLT3LG Recombinant Antibody (clone DS1324AB) (MOR-1324)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, IF, IHC-P, WB
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For Research Use Only. Not For Clinical Use.

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

Protein class

RAS pathway related proteins

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (T-cells, NK-cells)

Immune cell specificity

Group enriched (T-reg, naive CD4 T-cell, memory CD4 T-cell, MAIT T-cell, naive CD8 T-cell, memory CD8 T-cell, gdT-cell)

Cell line specificity

Cell line enhanced (HDLM-2, U-266/70)

Interaction

Homodimer (isoform 2).

Molecular function

Cytokine

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