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FOXP3
Loading...Anti-FOXP3 Products
- Rabbit Anti-FOXP3 Recombinant Antibody (clone JF0898) (MRO-0606-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, FC
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- Rabbit Anti-FOXP3 Recombinant Antibody (clone JF0926) (MRO-0607-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Recombinant Mouse Anti-FOXP3 Antibody (VS-0923-FY61) (VS-0923-FY61)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: ELISA, WB
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- AbPlus™ Anti-FOXP3 Magnetic Beads (VS-0724-YC757) (VS-0724-YC757)
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- Target: FOXP3
- Target Species: Human
- Application: IP, Protein Purification
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- Human Anti-FOXP3 Recombinant Antibody (HPAB-M0274-YC) (HPAB-M0274-YC)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: FC
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- Human Anti-FOXP3 Recombinant Antibody; scFv Fragment (HPAB-M0274-YC-S(P)) (HPAB-M0274-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Human Anti-FOXP3 Recombinant Antibody; Fab Fragment (HPAB-M0274-YC-F(E)) (HPAB-M0274-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
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- Mouse Anti-NHP FOXP3 Recombinant Antibody (clone SPM579) (VS-1024-XY207)
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- Species Reactivity: Human, Mouse, Non-human primate
- Type: Mouse IgG1, kappa
- Application: WB, IHC, FC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Anti-Mouse FOXP3 Immunohistochemistry Kit (VS-0525-XY2643)
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- Species Reactivity: Human, Mouse
- Target: FOXP3
- Application: IHC
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB, IHC-p, IF, ICC, ELISA
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- Anti-FOXP3 Immunohistochemistry Kit (VS-0325-XY862)
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- Species Reactivity: Human
- Target: FOXP3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (T-cells, Horizontal cells, Melanocytes, Hepatocytes, granulocytes)
Immune cell specificity
Immune cell enriched (T-reg)
Cell line specificity
Cell line enhanced (HDLM-2, MCF7, SiHa)
Interaction
Homodimer (PubMed:21458306, PubMed:25567984). Dimerization is essential for its transcriptional regulator activity (PubMed:21458306). Interacts with IKZF3. Isoform 1 (via LXXLL motif), but not isoform 2, interacts with isoform 4 of RORA (via AF-2 motif). Interacts with STUB1, HSPA8 and HSPA1A/B. Interacts with PPP1CA, PPP1CB and PPP1CG. Interacts with KAT5 and HDAC7. Interacts with HDAC9 in the absence of T-cell stimulation. Interacts with USP7. Interacts with isoform 2 of ZFP90 and can form a complex with TRIM28 in the presence of isoform 2 of ZFP90. Interacts with RUNX1. Interacts with RORC. Interacts with RELA and NFATC2. Interacts with RUNX2, RUNX3 and IKZF4 (By similarity).
Molecular function
Activator, DNA-binding, Repressor
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Related Diseases
Inflammatory Bowel Diseases