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FTCD
Anti-FTCD Recombinant Antibody Products
- AbPlus™ Anti-FTCD Magnetic Beads (VS-0724-YC161) (VS-0724-YC161)
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- Target: FTCD
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-FTCD Immunohistochemistry Kit (VS-0325-XY867)
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- Species Reactivity: Human, Rat
- Target: FTCD
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Hepatocytes, Proximal tubular cells, Cholangiocytes, Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (Hep G2)
Interaction
Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
Molecular function
Lyase, Multifunctional enzyme, Transferase
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