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FZD10
Anti-FZD10 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
Protein class
CD markers, G-protein coupled receptors
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Squamous epithelial cells, Skeletal myocytes, Basal squamous epithelial cells, Smooth muscle cells, Suprabasal keratinocytes, Basal keratinocytes, Fibroblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, BEWO, hTCEpi, RPTEC TERT1, RT4)
Interaction
Interacts with WNT7B (By similarity). Interacts with MYOC (PubMed:19188438).
Molecular function
Developmental protein, G-protein coupled receptor, Receptor, Transducer
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