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FcγRII & LDL

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Anti-FcγRII & LDL Products

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For Research Use Only. Not For Clinical Use.


Low-density lipoprotein (LDL) is one of the two main types of lipoproteins that carry cholesterol in the blood. It's often referred to as "bad" cholesterol because high levels can contribute to the buildup of plaque in the arteries, increasing the risk of heart disease and stroke.
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
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