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GYPA
Anti-GYPA Recombinant Antibody Products
- Mouse Anti-GYPA Recombinant Antibody (TAB-150CT) (TAB-150CT)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Funcs, PD, PK, ELISA
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- Mouse Anti-GYPA Recombinant Antibody; scFv Fragment (TAB-150CT-S(P)) (TAB-150CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-GYPA Recombinant Antibody; Fab Fragment (TAB-150CT-F(E)) (TAB-150CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Human Anti-GYPA Recombinant Antibody (TAB-151CT) (TAB-151CT)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: VHH
- Application: ELISA, FC, WB
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For Research Use Only. Not For Clinical Use.
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
Protein class
Blood group antigen proteins, CD markers
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Erythroid cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEL, K-562)
Interaction
Homodimer. (Microbial infection) Interacts with Streptococcus gordonii hsa protein.
Molecular function
Blood group antigen, Host cell receptor for virus entry, Receptor
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