HAV Surface Antigen

Hepatitis a surface antigen is a substance that always induces the production of hepatitis a antibodies in the body. Hepatitis A virus (HAV) is an icosahedral solid symmetric spherical particle with A diameter of 27 to 32nm without an envelope, with A core of single-stranded forward RNA. HAV is a small RNA virus family hepatoviruses or heparnaviruses. HAV is transmitted mainly through the hand-mouth channel with an incubation period of 15-50 days, averaging 28 days. The virus often exists in the patient's blood and feces 5-6 days before the elevation of ALT in the patient's serum. Two to three weeks after the onset of the disease, with the production of specific antibodies in the serum, serum and fecal infectious gradually disappear. Laboratory diagnosis of HAV allows for antigen detection.

Because the monoclonal antibody at different binding sites can improve the sensitivity of reagents and the specificity of polyclonal antibody is better, the polyclonal antibody or polyclonal antibody can be used to obtain the high sensitivity and specificity of the surface antigen detection reagent for the study and production of the inactivated vaccine of hepatitis a.

It can be used for the qualitative and quantitative detection of surface antigen of hepatitis a.