HIV-1 Vif

Tetramer Products Formats

Anti-HIV-1 Vif Recombinant Antibody Products

PE-A*02:01/HIV-1 Vif (GLADQLIHL) MHC Tetramer (MHC-LC254)
- Class: Class I
- Antigen: HIV-1 Vif
- Antigen Species: HIV-1
- Peptide: GLADQLIHL
- Conjugate: PE
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APC-A*02:01/HIV-1 Vif (GLADQLIHL) MHC Tetramer (MHC-LC255)
- Class: Class I
- Antigen: HIV-1 Vif
- Antigen Species: HIV-1
- Peptide: GLADQLIHL
- Conjugate: APC
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BV421-A*02:01/HIV-1 Vif (GLADQLIHL) MHC Tetramer (MHC-LC256)
- Class: Class I
- Antigen: HIV-1 Vif
- Antigen Species: HIV-1
- Peptide: GLADQLIHL
- Conjugate: BV421
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For Research Use Only. Not For Clinical Use.

HIV-1 Vif (viral infectivity factor), supports productive viral replication in non-permissive cells, such as peripheral blood lymphocytes. It functions by inactivating a cellular anti-viral factor named APOBEC3G. Vif binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology. Interacts with host ABCE1, which seems to be involved in lentiviruses capsid formation and displays RNase L inhibitor activity. This interaction may play a role in protecting viral RNA from damage during viral assembly.