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HIV-1 Vif
Anti-HIV-1 Vif Recombinant Antibody Products
- Human Anti-HIV-1 Vif Recombinant Antibody (clone J4) (MRO-4329CQ)
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- Derivation: Humanized
- Species Reactivity: HIV-1
- Type: Humanized IgG
- Application: WB, ELISA, Neut, IF, Inhib
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- Human Anti-HIV-1 Vif Recombinant Antibody (clone J4); scFv Fragment (MRO-4329CQ-S(P))
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- Derivation: Humanized
- Species Reactivity: HIV-1
- Type: Humanized scFv
- Application: ELISA, IF, WB
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- Mouse Anti-HIV-1 Vif Recombinant Antibody (clone TG002); scFv Fragment (MRO-4330CQ-S(P))
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- Species Reactivity: HIV-1
- Type: Mouse scFv
- Application: ELISA
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- Human Anti-HIV-1 Vif Recombinant Antibody (clone J4); Fab Fragment (MRO-4329CQ-F(E))
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- Derivation: Humanized
- Species Reactivity: HIV-1
- Type: Humanized Fab
- Application: ELISA, IF, WB
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- Mouse Anti-HIV-1 Vif Recombinant Antibody (clone TG002); Fab Fragment (MRO-4330CQ-F(E))
-
- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
HIV-1 Vif (viral infectivity factor), supports productive viral replication in non-permissive cells, such as peripheral blood lymphocytes. It functions by inactivating a cellular anti-viral factor named APOBEC3G. Vif binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology. Interacts with host ABCE1, which seems to be involved in lentiviruses capsid formation and displays RNase L inhibitor activity. This interaction may play a role in protecting viral RNA from damage during viral assembly.