HLA-A2

Creative Biolabs provides a comprehensive selection of high-quality anti-HLA-A2 recombinant antibodies, specifically designed to meet the rigorous demands of modern research and therapeutic applications. Each antibody in our collection is meticulously engineered using our advanced recombinant technology, ensuring unparalleled specificity and stability. These antibodies are essential tools for researchers focused on the intricate mechanisms of immune response, particularly in the context of targeted cancer therapy. With excellent binding affinity and functional performance, our anti-HLA-A2 antibodies empower scientists to explore innovative treatments and enhance the understanding of immune evasion in tumors.

HLA-A2: A Crucial Target for Cancer Treatment

HLA-A2 is a vital human leukocyte antigen (HLA) due to its high occurrence in the population and its essential role in presenting antigens to T cells, which is crucial for initiating immune responses. Its function is especially significant in cancer immunotherapy, where HLA-A2 serves as a target for developing cancer vaccines and T-cell therapies. These strategies attempt to activate the immune system to detect and destroy tumor cells containing HLA-A2-bound tumor-specific antigens, improving therapeutic efficacy and opening the path for individualized cancer treatment.

Alternative Names

HLA-A; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen; Major histocompatibility complex, class I, A; HLAA; Antigen-presenting molecule; leukocyte antigen class I-A.

Background

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.

Anti-HLA-A2 rAb Products

Creative Biolabs provides highly customized anti-HLA-A2 recombinant antibody products for sophisticated research and therapeutic applications. These antibodies are specially designed to target the HLA-A2 antigen, which is an important component of the immune response and a major participant in many disorders, including cancer. Our recombinant antibodies have great specificity and affinity, delivering accurate and consistent findings in your research. These products, which are manufactured using cutting-edge technology, are appropriate for a wide range of applications, including flow cytometry, immunohistochemistry, ELISA, etc. Creative Biolabs' strict quality control techniques provide the greatest purity and performance, allowing researchers to investigate immunological pathways and create novel treatment solutions.

Table 1. Featured anti-HLA-A2 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs provides a wide selection of anti-HLA-A2 recombinant antibodies that are precisely produced to the highest quality standards. Our cutting-edge facilities and experienced scientists are dedicated to designing each antibody precisely, guaranteeing that it targets HLA-A2 with extraordinary precision. We ensure that our antibodies have great specificity, strong binding affinity, and perfect optical properties, making them suitable for a wide range of research applications.

Customer Reviews

Excellent

An***d***i
Human Anti-HLA-A2 Recombinant Antibody (clone 3PF12) (FAMAB-0158JF)

As a researcher, I often need high-quality antibodies to ensure the accuracy of experiments. The anti-HLA-A2 recombinant antibodies provided by Creative Biolabs are not only of high quality, but also have a wide range of applications, which is very suitable for our research needs. We have used them in multiple projects and the results are very ideal.

11/Sep/2023

Excellent

Cr***l
Mouse Anti-HLA-A2 Recombinant Antibody (clone G1) (FAMAB-0167YC)

I am impressed by the anti-HLA-A2 antibodies from Creative Biolabs. The quality of each batch of products remains stable, and the reproducibility of experimental results is satisfactory after use. These antibodies performed excellently in our cell experiments and are recommended.

19/Nov/2023

Excellent

Ap***r
Human Anti-HLA-A2 Recombinant Antibody (clone 3PF12) (FAMAB-0158JF)

I am very satisfied with the anti-HLA-A2 recombinant antibodies from Creative Biolabs. Their specificity and binding affinity are excellent, which makes our experimental results more reliable. More importantly, the customer service team is very professional and responds to all our questions quickly, which makes our research progress smoother.

24/Nov/2023

rAb Production

Creative Biolabs offers a reliable range of high-quality anti-HLA-A2 antibodies, expertly engineered using advanced genetic techniques to ensure optimal performance in various research applications.

Featured Anti-HLA-A2 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-HLA-A2 recombinant antibody production.

Fig.2 Gram-scale anti-HLA-A2 recombinant antibody production.

rAb Modalities

Creative Biolabs offers an extensive selection of premium anti-HLA-A2 recombinant antibodies, available in multiple formats to cater to the diverse needs of researchers worldwide.

Fig.3 Full-length anti-HLA-A2 recombinant antibody production and modalities.

HLA-A2-Targeted Drug Information

Table 2. Public drug targeting HLA-A2.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is a prominent biological research service firm, specializing in offering high-quality laboratory supplies and solutions to researchers throughout the globe. In our expanding product line, the Anti-HLA-A2 recombinant antibody series is a highlight. These antibodies are targeted at HLA-A2 antigens, have high specificity and affinity, and are widely used in research in immunology, oncology, and related fields. If you are interested in our anti-HLA-A2 recombinant antibody products, please get in touch with us without hesitation.