HPV L1
Anti-HPV L1 Recombinant Antibody Products
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- Derivation: Human
- Species Reactivity: HPV
- Type: IgG
- Application: WB, IP, FuncS
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- Derivation: Mouse
- Species Reactivity: HPV
- Type: IgG
- Application: ELISA, WB, FC, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, ELISA
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- Species Reactivity: HPV
- Type: Mouse IgG
- Application: ELISA, Neut
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- Species Reactivity: HPV
- Type: Mouse IgG
- Application: ELISA, WB
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- Species Reactivity: HPV
- Type: Mouse IgG
- Application: ELISA, Neut
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Derivation: Mouse
- Species Reactivity: HPV
- Type: Fab
- Application: IF, FuncS
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- Derivation: Mouse
- Species Reactivity: HPV
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
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- Derivation: Human
- Species Reactivity: HPV
- Type: Fab
- Application: FC, WB, FuncS
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- Derivation: Human
- Species Reactivity: HPV
- Type: scFv
- Application: ELISA, WB, FC, FuncS
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- Species Reactivity: HPV
- Type: Mouse scFv
- Application: ELISA, Neut
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- Species Reactivity: HPV
- Type: Mouse scFv
- Application: ELISA, WB
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- Species Reactivity: HPV
- Type: Mouse scFv
- Application: ELISA, Neut
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- Species Reactivity: HPV
- Type: Mouse Fab
- Application: ELISA, Neut
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- Species Reactivity: HPV
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: HPV
- Type: Mouse Fab
- Application: ELISA, Neut
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For Research Use Only. Not For Clinical Use.
L1 spontaneously self-assembles into pentameric capsomers. Purified capsomers can go on to form capsids, which are stabilized by disulfide bonds between neighboring L1 molecules. L1 capsids assembled in vitro are the basis of prophylactic vaccines against several HPV types. Compared to other papillomavirus genes, the amino acid sequences of most portions of L1 are well-conserved between types. However, the surface loops of L1 can differ substantially, even for different members of a particular papillomavirus species. This probably reflects a mechanism for evasion of neutralizing antibody responses elicited by previous papillomavirus infections.