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HTR1B
Anti-HTR1B Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.
Protein class
FDA approved drug targets, G-protein coupled receptors, Transporters
Predicted location
Membrane
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HUVEC TERT2, TIME)
Interaction
Homodimer. Heterodimer with HTR1D.
Molecular function
G-protein coupled receptor, Receptor, Transducer
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