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Hc
Anti-Hc Recombinant Antibody Products
- Rat Anti-Hc Recombinant Antibody (NEUT-091CQ) (NEUT-091CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: Neut, WB
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- Rat Anti-Hc Recombinant Antibody (clone CBL857) (NEUT-092CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Neut, WB
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For Research Use Only. Not For Clinical Use.
The tetanus toxin protein has a molecular weight of 150kDa. It is translated from the tetX gene as one protein which is subsequently cleaved into two parts: a 100kDa heavy chain and a 50kDa light chain. The chains are connected by a disulfide bond. The B-chain binds to dissialogangliosides (GD2 and GD1b) on the neuronal membrane and contains a translocation domain which aids the movement of the protein across that membrane and into the neuron.