Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
+ Filter
Loading...
Custom Services order now ship next day

IL3RA

Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibody Products AbPlus Recombinant Antibody Products Functional Antibody Products Formats Research Area

Anti-IL3RA Recombinant Antibody Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
Protein class

CD markers, FDA approved drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (dendritic cells, Endothelial cells, Adipocytes, monocytes, Langerhans cells)

Immune cell specificity

Immune cell enriched (basophil)

Cell line specificity

Cell line enhanced (HDLM-2, NB-4, RPMI-8226)

Interaction

Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.

Molecular function

Receptor

More Types Infomation
  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare