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INHBB
Anti-INHBB Recombinant Antibody Products
- Mouse Anti-INHBB Antibody, mRNA (TAB-440CL-mRNA)
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- Species Reactivity: Human
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- Rabbit Anti-INHBB Recombinant Antibody (VS13-YC588) (VS13-YC588)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016]
Protein class
Cancer-related genes
Predicted location
Secreted
Single cell type specificity
Group enriched (Granulosa cells, Adipocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A549, ASC diff, BJ hTERT+ SV40 Large T+ RasG12V, MCF7, PC-3, SK-BR-3, T-47d)
Interaction
Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3.
Molecular function
Growth factor, Hormone
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