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ITFG2
Anti-ITFG2 Recombinant Antibody Products
- Mouse Anti-NHP ITFG2 Recombinant Antibody (clone OTI3A3) (VS-1024-XY287)
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- Species Reactivity: Human, Non-human primate, Rat
- Type: Mouse IgG1
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.
Involved in cellular response to amino acid starvation; cellular response to glucose starvation; and negative regulation of TORC1 signaling. Located in lysosomal membrane. Part of KICSTOR complex.
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Part of the KICSTOR complex composed of KPTN, ITFG2, KICS2 and SZT2. SZT2 probably serves as a link between the other three proteins in the KICSTOR complex and may mediate the direct interaction with the GATOR complex via GATOR1. The KICSTOR complex interacts directly with the GATOR1 complex and most probably indirectly with the GATOR2 complex in an amino acid-independent manner.
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