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ITGB1
Engineered Antibody Products
Antibody Magnetic Beads
Cancer Stem Cell Biomarker Specific Antibody Products
AbPlus
Recombinant Antibody Products
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Anti-ITGB1 Recombinant Antibody Products
- Anti-Integrin-SPDB-DM4 ADC (ADC-030LZY)
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- Target: Integrin
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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For Research Use Only. Not For Clinical Use.
ITGB1 encodes the beta-1 subunit of integrin receptors, which mediate cell adhesion to the extracellular matrix and are involved in processes such as migration, signaling, and tissue repair. Integrins are crucial for immune system function, wound healing, and embryonic development. ITGB1 is expressed in nearly all cell types and binds to extracellular matrix components like fibronectin and collagen. Mutations in ITGB1 can lead to various disorders, including developmental defects, chronic inflammation, and impaired wound healing.