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JCHAIN

Anti-JCHAIN Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


JCHAIN (Joining Chain Of Multimeric IgA And IgM) is a Protein Coding gene. Diseases associated with JCHAIN include Alpha Chain Disease and Mu Chain Disease. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Cell surface interactions at the vascular wall. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and antigen binding.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enriched (Plasma cells)

Immune cell specificity

Group enriched (memory B-cell, plasmacytoid DC, naive B-cell)

Cell line specificity

Cell line enhanced (Daudi, Karpas-707, RPMI-8226, U-266/70, U-266/84, U-698)

Interaction

Part of the secretory IgA (sIgA) complex that consists of two, four or five IgA monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteoytic product of PIGR).

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