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KIF21A

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Anti-KIF21A Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cone photoreceptor cells, Bipolar cells, Inhibitory neurons)

Immune cell specificity

Group enriched (memory CD8 T-cell, gdT-cell, naive CD8 T-cell, memory CD4 T-cell, MAIT T-cell, NK-cell, T-reg)

Cell line specificity

Cell line enriched (SH-SY5Y)

Interaction

Interacts (via residues 1146-1167) with KANK1 (via ankyrin repeats 1-5) and KANK2 (via ankyrin repeats 1-5).

Molecular function

Motor protein

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