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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes
Intracellular
Low cell type specificity
Immune cell enriched (plasmacytoid DC)
Low cell line specificity
Part of the KICSTOR complex composed of KPTN, ITFG2, KICS2 and SZT2. SZT2 probably serves as a link between the other three proteins in the KICSTOR complex and mediates the direct interaction with the GATOR1 complex (PubMed:28199306). May associate with F-actin filaments (PubMed:10099934).
Actin-binding