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LAMB2
Anti-LAMB2 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ICC, IF, IHC, IP
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- Recombinant Mouse Anti-LAMB2 Antibody (VS-0923-FY202) (VS-0923-FY202)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.
Laminin subunit beta-2 is a protein encoded by the LAMB2 gene in humans. Laminin is a family of extracellular matrix glycoproteins and the main non-collagen component of the basement membrane. They are involved in a variety of biological processes, including cell adhesion, differentiation, migration, signaling, and neurite outgrowth and metastasis.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Leydig cells, Peritubular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (fHDF/TERT166)
Interaction
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-2 is a subunit of laminin-3 (laminin-121 or S-laminin), laminin-4 (laminin-221 or S-merosin), laminin-7 (laminin-321 or KS-laminin), laminin-9 (laminin-421), laminin-11 (laminin-521), laminin-14 (laminin-423) and laminin-15 (laminin-523).
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