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LAMP3

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For Research Use Only. Not For Clinical Use.


Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses.
Protein class

CD markers

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Alveolar cells type 2, monocytes)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Group enriched (EFO-21, HDLM-2, HHSteC, hTCEpi, JURKAT)

Interaction

Monomer (PubMed:22809326). Interacts with FURIN (PubMed:32295904). (Microbial infection) Interacts with mumps virus protein F; this interaction promotes protein F cleavage by FURIN.

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