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LGSN

MHC
This gene encodes a protein with similarity to the GS I members of the glutamine synthetase superfamily. The encoded protein is referred to as a pseudo-glutamine synthetase because it has no glutamine synthesis activity and may function as a chaperone protein. This protein is localized to the lens and may be associated with cataract disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Proximal tubular cells, Late spermatids, Inhibitory neurons, Excitatory neurons, Respiratory ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A549, BEWO, CACO-2, HeLa, Karpas-707)

Interaction

Dodecamer. Interacts with BFSP2 AND VIM (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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