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MAGEA1
Anti-MAGEA1 Recombinant Antibody Products
- Anti-MAGEA1 immunotoxin (scFv)-ABR (AGTO-G048A)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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For Research Use Only. Not For Clinical Use.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Spermatogonia, Spermatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEL, HMC-1, RPMI-8226, U-2 OS, U-266/70, U-266/84)
Interaction
Interacts with SNW1 and HDCA1.
Molecular function
Tumor antigen
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