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MGEA5
Anti-MGEA5 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (dendritic cells, Collecting duct cells, Glandular and luminal cells, Pancreatic endocrine cells, Granulosa cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:11788610). Interacts with CLOCK (By similarity). (Microbial infection) Interacts with human T-cell leukemia virus 1/HTLV-1 protein Tax; this interaction increases Tax interacting partner CREB1 O-GlcNAcylation.
Molecular function
Glycosidase, Hydrolase
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