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MYL2
Anti-MYL2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Protein class
Candidate cardiovascular disease genes, Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Group enriched (naive B-cell, memory B-cell)
Cell line specificity
Cell line enhanced (EFO-21, HSkMC, U-2 OS)
Interaction
Myosin is a hexamer of 2 heavy chains and 4 light chains. Interacts with MYOC (PubMed:11773029).
Molecular function
Motor protein, Muscle protein, Myosin
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